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Hakim Health Sys Res 2006, 8(4): 21-25 Back to browse issues page
Monitoring therapeutic efficacy of chloroquine on uncomplicated Plasmodium falciparum in Iran.
Abstract:   (21926 Views)

 Introduction: Malaria is still one of the important parasitic diseases aroud the country and the major health problem in south – east of Iran.

 Methods: Based on the role of therapeutic effect and importance of failure rate of antimalaria drugs in national drug policy a joint study with collaboration of WHO on montoring of therapeutic efficacy of chloroqine has been done according to the latest WHO guideline in south & southeast provinces َin 2002-03.

 Results: According to the findings, from 144 uncomplicated cases who were eligible for 28 days follow up, only 21.5 % showed adequate clinical & parasitological response to chloroquine (ACPR), 17.4% showed early treatment failure ( ETF ) , 34.7% late clinical failure and 26.4% late parasitologcal failure (LPF).

 Conclusion: Based on the results, drug changing the first line antimalaria drug regimen is recommended for treatment of uncomplicated falciparum malaria.

 

 Hakim Research Journal 2006 8(4) 21-25.

Keywords: falciparum malaria, efficacy, chloroquine
Full-Text [PDF 244 kb]   (2566 Downloads)    
Type of Study: Original | Subject: General
Received: 2006/09/6
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Monitoring therapeutic efficacy of chloroquine on uncomplicated Plasmodium falciparum in Iran. . Hakim Health Sys Res . 2006; 8 (4) :21-25
URL: http://hakim.hbi.ir/article-1-307-en.html


Volume 8, Issue 4 (Dec 2006) Back to browse issues page
فصلنامه پژوهش حکیم Hakim Research Journal
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